As a result we have now looked systematically across the modelling of a range of conditions including spinal cord injury, multiple sclerosis, cerebral glioma, Parkinson's disease, Huntington's disease and Alzheimers disease; many of these are either published or in press.
Broadley speaking, our hypothesis that findings in these domains might similarly be confounded by poor study quality has been confirmed.
This has been reflected in the recent report from the Nuffield Council on Bioethics, "The Ethics of Research Involving Animals", which recommends...
CAMARADES began as the "Collaborrative Approach to Meta-Analysis and Review of Animal Data from Experimental Stroke", refelecting the interests of the investigators in translational failure in Stroke.
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The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies.
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The proposed research is therefore crucial to the development of "reduction"strategies.It seems likely that similar issues might confound animal modelling of non-neurological disease, or indeed more fundamental research in the life sciences.This is an increasing focus of our current work, and to reflect this we have decided to change the S of CAMARADES from "Stroke" to "Studies".Harry Blackburn has a special way of reminding his grandchildren just who's boss.He plays Wii bowling with them -- and wins every time.